Index

279

alpha-synuclein, 54

clinical manifestations, 10

clinical trials in PD, 55

diagnosis, 10

bradykinesia, 10

dopaminergic neurons, 54

levodopa, 54

Lewy bodies, 10, 54

mathematical model, 167

microarray studies, 206

organoids in PD, 55

PSCs in PD, 54

RNA-seq studies, 210

treatments, 11

Perl, 199

PET, 185

power, 181

predictive oncology, 164

programming languages

C++, 152

Perl, 199

Python, 199

R programming, 199

proteomics, 250

biofluids, 261

brain proteomics, 250

clinical

proteomics, 258

large-scale proteomic, 251

localized proteomics, 258

MS-based proteomics, 263

organelle proteomics, 261

shotgun proteomics, 251, 252

proteomics approaches

bottom-up, 253

top-down, 253

Python, 199, 257

R

R programming, 199, 257

reaction diffusion equations

(RDE) for modeling

brain tumors, 145

reaction models, 145

REACTOME, 256

repositories, 202

ArrayExpress, 202

DDBJ, 202

DisGeNET, 204

GAD, 204

Gene Expression Omnibus

(GEO), 202

OMIM, 204

RNA-seq technologies

gene expression, 201

NGS, 201

PCR, 201

S

scaffold-free models

biobanking, 94

drug response, 90

immunotherapy, 93

tumor biology, 87

schizophrenia, 21, 185, 207, 210,

241, 261, 263

connectome, 241

microarray studies, 207

RNA-seq studies, 210

treatment, 21

secondary autism, 25

sEEG, 177

spatiotemporal brain model, 212

spatiotemporal tumor model, 145

spectral clustering, 234

SSVEP, 179

stem cell niche, 44

stem cells, 43

induced pluripotent stem

cells, 47

somatic cell

reprogramming, 47

adult stem cells, 44

hematopoietic stem cells,

47

mesenchymal stem cells, 45

MSC functions, 45

neural stem cells, 46

neurogenesis, 46

NSC niches, 46